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Man in his forties sitting up rested at the edge of the bed in cool violet dawn light, calm and renewed.

Growth hormone works while you sleep.

New protocolPhysician-guided GHRH peptide therapy

Growth-hormone peptides

  • Prompts your own pituitary to release growth hormone in its natural nightly pulses — not a constant synthetic flood.
  • Made for deeper sleep, easier recovery, and leaner body composition as your IGF-1 comes up.
  • A bedtime routine you can actually keep — injection, nasal spray, or under-the-tongue troche.
Monthly supplyBedtime protocol
$194.99/mo
Choose your format
Injection · Nasal · Troche
Check your eligibility
FSA & HSA eligibleUse eligible benefit funds
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Free discreet shipping
Licensed US compounding pharmacies
US-licensed providers

Pricing varies by format and dose. Your provider sets the dose from your visit. See full pricing →

Best for

Adults who want deeper sleep, faster recovery, and leaner body composition by raising their own growth hormone — not replacing it with synthetic HGH.

A man and a woman standing together, looking at each other
For men and women
Improve cognitive performance
Recover faster
Restore vitality & drive
Burn stubborn fat
Support collagen for firmer skin
Strengthen hair & nails
Sleep deeper
Support bone health
Manage weight more easily
Available formats

Choose injection, spray,
or troche.

Injection, nasal spray, and troches differ by price, dose flexibility, routine, storage, travel, supply, and follow-up needs.

Sermorelin injectable — unbranded product
Injectable
from $194.99/mo
Subcutaneous injection with syringe prep, storage, and dose timing set by the prescription.
Sermorelin nasal spray — unbranded product
Nasal spray
$289.99/mo
Needle-free metered spray routine with a 6 mL monthly supply and no syringe prep.
Sermorelin sublingual troches — unbranded product
Sublingual troches
$289.99/mo
Dissolves under the tongue when a nightly mouth-dissolve routine is easier than sprays or injections.

Reduce fat. Recover faster. Rejuvenate naturally.

Sermorelin — deeper sleep is often the first thing people notice

How Growth Hormone peptides work

From your first dose to full systemic benefits — here’s exactly what happens inside your body at each stage of the process.

Sermorelin nasal spray bottle on a cobalt track-inspired surface
Step 1

Nasal spray routine

A needle-free spray format for nights when the routine needs to stay simple.

Profile of a person with a luminous signal overlay tracing to the pituitary
Step 2

Pituitary activation

The peptide signals your pituitary gland—the master regulator of hormones—to release growth hormone in natural pulses.

Amber glass orbs converting along a luminous signal path to cobalt orbs, representing GH to IGF-1 conversion
Step 3

GH → IGF-1 conversion

Growth hormone travels to your liver and triggers the production of IGF-1 (insulin-like growth factor), the molecule responsible for most of GH’s downstream benefits.

Athlete running on a cobalt track in hard sunlight
Step 4

Systemic benefits

Elevated IGF-1 drives fat metabolism, accelerates tissue repair, improves skin and hair quality, enhances sleep architecture, and supports overall vitality.

Why it matters with age

Your growth hormone fades with age.

Your pituitary keeps working, but the nightly growth-hormone pulses shrink decade by decade — one reason sleep, recovery, and body composition tend to drift as you get older. Sermorelin works one step upstream to nudge that rhythm back up.

Five translucent glass human figurines in a row, shrinking from the 20s to the 60s+, each with a violet glow at its core that dims and descends along a dotted signal line — illustrating how growth-hormone rhythm fades with age.
Night-pulse amplitude drops with ageYour review starts with sleep, history, and route

Your rhythm, not a constant flood

  • Synthetic HGH holds growth hormone at a flat, outside level and switches off your body's own controls.
  • Sermorelin prompts your pituitary to release growth hormone in the natural nightly pulses your body already uses.
  • Your feedback loop stays intact — production self-regulates, which is a big part of the more favorable safety profile. Individual results vary.¹²
Compare the three formats →
Illustrative growth-hormone release over a night: a glowing violet liquid-glass wave labeled 'Your own nightly pulses' rises and falls, above a flat dotted line labeled 'Synthetic HGH: constant level'. Schematic, not patient data.

The biology, up close

What's happening inside the cell.

Sermorelin doesn't add growth hormone from the outside — it works one signal upstream, coaxing your own cells to do what they already know how to do. Here's the chain, from the pituitary to the tissue.

Editorial macro of glowing violet neuroendocrine pituitary cells releasing pulses of light.Stage 01 · The signal

A nudge to the pituitary

Sermorelin binds GHRH receptors on the pituitary's somatotroph cells and tells them to fire — the same trigger your own hypothalamus uses, just reinforced.

Editorial macro of luminous growth-hormone molecules traveling through a warm-lit blood vessel.Stage 02 · The release

Growth hormone, in pulses

Those cells release growth hormone in short bursts into your bloodstream — a pulsatile rhythm, concentrated at night, that your feedback loop keeps in check.

Editorial macro of a cell surface with glowing IGF-1 receptors as tissue regenerates.Stage 03 · The payoff

IGF-1 at your tissues

Growth hormone reaches the liver and drives IGF-1, which meets receptors on muscle, skin, and bone cells to fuel repair, recovery, and renewal.

Backed by labs, not vibes

A real, measurable rise in IGF-1.

IGF-1 is the growth-hormone marker your provider can actually measure. In a placebo-controlled trial of a GHRH(1–29) analog — the same class as sermorelin — serum IGF-1 rose meaningfully over 16 weeks, while it stayed flat on placebo.

Growth hormone is released mainly during deep sleep, which is why deeper sleep and better recovery are usually the first changes people report.³

Check your eligibility
↑ 28%Higher IGF-1 (a growth-hormone marker) on sermorelin in trials
A partly filled glass cylinder of cobalt liquid beside an empty one: serum IGF-1 rose about 28% with sermorelin-class (GHRH 1-29) therapy over 16 weeks, versus no meaningful change during the placebo phase.
GHRH(1–29)-analog RCT in adults 55–71, n=19, 16 weeks (Khorram 1997)Sermorelin is compounded; the cited trial used a GHRH(1–29) analog. Objective serum lab metric, not a sleep-stage claim.Source: Khorram 1997 (J Clin Endocrinol Metab)
Calm bedtime scene: a warm lamp and a glass of water on a nightstand in low violet evening light.

One step, right before bed.

Sermorelin fits into the moment you're already in — a quick dose at bedtime, timed to your body's own nighttime growth-hormone release. No mid-day planning, no complicated routine to keep up.

Check your eligibility

GHRH peptides vs. synthetic HGH

RebodySermorelin
Synthetic HGH
Where the growth hormone comes fromThe source of the hormone in your body.
Your own pituitary
Injected from outside
Release patternHow the hormone moves through your day.
Natural nightly pulses
Constant, unregulated level
Your feedback loopWhether your body keeps self-regulating.
Stays intact
Overridden
RoutineWhat it actually looks like day to day.
Bedtime dose — 3 formats
Daily injections
Side-effect profileRelative risk of the common issues.
Generally lower
Higher (fluid, joints, glucose)
Check your eligibility

What the extra growth hormone actually does.

Woman sleeping in warm morning light with soft bedding and relaxed skin texture.

Sleep that carries into the morning

Man resting after strength training with a white towel in bright trackside light.

Recovery that keeps up with training

Older woman stretching outdoors against blue sky and prismatic morning light.

Leaner body composition, over time

Check your eligibility

It's easy to get started.

Man in a cobalt jacket viewing the Rebody mobile homepage on a smartphone.

01

Start your online visit

Share your sleep, recovery, energy, and any labs from your phone. It takes about five minutes — no appointment needed.

Woman in a yellow sweater holding a smartphone for a video visit with a provider.

02

A provider reviews your fit

A licensed provider checks your history and medications, confirms you're a good candidate, and recommends an injection, nasal spray, or troche with the appropriate dose.

A hand lifting an unbranded purple Sermorelin troche jar from a discreet kraft delivery box in warm morning light.

03

Delivered to your door

If prescribed, your sermorelin ships discreetly with everything you need. Message your care team about refills, timing, and dose changes anytime.

Check your eligibility
Adult resting after training in cool light, wet skin and glass refraction.

Start your online visit

Share sleep timing, fatigue pattern, medications, diagnoses, prior treatment use, and whether injection, nasal spray, or troches match your routine.

Start your online visitfrom$289.99/mo$194.99/moSave $95

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See what the online visit asks

Growth-hormone peptide FAQs

Contact support →
What are growth-hormone peptides, and how do they work?

Sermorelin is a GHRH peptide — a secretagogue. Instead of replacing growth hormone the way synthetic HGH does, it signals your pituitary to release more of your own, in the natural nighttime pulses your body already uses. Your feedback loop stays intact, which is a big part of why the safety profile is more favorable than HGH.

How is this different from synthetic HGH?

Synthetic HGH floods your system with a constant, outside dose and bypasses your body's own controls. Sermorelin works with those controls — your production self-regulates. You get the benefits of higher growth hormone without overriding your natural safety systems.

When will I notice a change?

Many people notice deeper sleep first, often within the first few weeks, since growth hormone is released mainly during deep sleep. Recovery, body composition, and skin changes build more gradually over three to six months of consistent nightly use. Individual response varies.

Which format is right for me — injection, nasal spray, or troche?

The injection offers the most dose flexibility. The nasal spray and under-the-tongue troche keep the routine needle-free. Your provider helps you choose based on your sleep timing, medications, and what you'll realistically keep up each night.

Do I need a prescription?

Yes. Sermorelin is prescription-only. When you finish your online visit, a licensed provider reviews your health profile and decides whether it's a good fit. If approved, your prescription is sent to a licensed US compounding pharmacy and shipped to you — no in-person visit required.

How do I take the injection?

It's a small subcutaneous injection just under the skin, usually in the upper outer thigh, taken at bedtime to line up with your body's natural nighttime growth-hormone release. Most people describe it as nearly painless. Full directions and message-based support come with your protocol.

Care you can trust, on your nightstand.

Sermorelin in your chosen format, listed prices, and a care team you can message — no clinics, no grey-market vials, and starting at $194.99/mo.

  • Online visits from your phone
  • US-licensed medical providers
  • LegitScript-certified US pharmacies
  • Free discreet shipping
Check your eligibility

What to know about side effects

Because sermorelin works through your body's own feedback loops, it has a more favorable side-effect profile than synthetic HGH. Most effects are mild and tend to ease as your body adjusts.

This is not a complete list. Message your care team with any questions.

Most common

  • Injection-site redness, itching, or swelling
  • Headache
  • Flushing or lightheadedness
  • Temporary water retention
  • Nasal irritation (nasal spray)
  • Odd taste (troche)

Less common — tell your provider

  • Persistent joint pain or stiffness
  • Marked swelling or fluid retention
  • Signs of high blood sugar — unusual thirst or frequent urination
  • Allergic reaction: rash, itching, or swelling

Important: Growth-hormone peptides are not for anyone with active or a history of cancer, during pregnancy or breastfeeding, or under 18. Tell your provider about every medication and supplement you take and any history of diabetes, thyroid, or pituitary conditions.

COMPOUNDED MEDICATIONS ARE NOT APPROVED OR EVALUATED FOR SAFETY, EFFICACY, OR QUALITY BY THE FDA.

  1. 1Khorram O, et al. Effects of a GHRH(1–29) analog on serum IGF-1 and body composition in older adults: a randomized, placebo-controlled trial. Journal of Clinical Endocrinology & Metabolism. 1997.
  2. 2Walker RF. Sermorelin: a better approach to management of adult-onset growth hormone insufficiency? Clinical Interventions in Aging. 2006.
  3. 3Van Cauter E, Plat L. Physiology of growth hormone secretion during sleep. Journal of Pediatrics. 1996.